Mapping the Ligand-Binding Region of Borrelia hermsii Fibronectin-Binding Protein

@inproceedings{Brenner2013MappingTL,
  title={Mapping the Ligand-Binding Region of Borrelia hermsii Fibronectin-Binding Protein},
  author={Christiane Brenner and Katharina Bomans and J{\"u}ri Habicht and Markus Michael Simon and Reinhard Wallich},
  booktitle={PloS one},
  year={2013}
}
Many pathogenic microorganisms express fibronectin-binding molecules that facilitate their adherence to the extracellular matrix and/or entry into mammalian cells. We have previously described a Borrelia recurrentis gene, cihC that encodes a 40-kDa surface receptor for both, fibronectin and the complement inhibitors C4bp and C1-Inh. We now provide evidence for the expression of a group of highly homologues surface proteins, termed FbpA, in three B. hermsii isolates and two tick-borne relapsing… CONTINUE READING
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