Mapping the Antigenic and Genetic Evolution of Influenza Virus

@article{Smith2004MappingTA,
  title={Mapping the Antigenic and Genetic Evolution of Influenza Virus},
  author={Derek J. Smith and Alan S. Lapedes and Jan C de Jong and Theo M. Bestebroer and Guus F Rimmelzwaan and Albert D M E Osterhaus and Ron A. M. Fouchier},
  journal={Science},
  year={2004},
  volume={305},
  pages={371 - 376}
}
  • Derek J. Smith, Alan S. Lapedes, +4 authors Ron A. M. Fouchier
  • Published 2004
  • Biology, Medicine
  • Science
  • The antigenic evolution of influenza A (H3N2) virus was quantified and visualized from its introduction into humans in 1968 to 2003. Although there was remarkable correspondence between antigenic and genetic evolution, significant differences were observed: Antigenic evolution was more punctuated than genetic evolution, and genetic change sometimes had a disproportionately large antigenic effect. The method readily allows monitoring of antigenic differences among vaccine and circulating strains… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 27 REFERENCES

    Am. J. Public Health

    • J E Salk, P C Suriano
    • Am. J. Public Health
    • 1949

    Avian Pathol

    • D J Alexander
    • Avian Pathol
    • 1997

    Gen. Virol

    • P A Underwood
    • Gen. Virol
    • 1982

    Hum. Factors

    • R Shepherd
    • Hum. Factors
    • 1963

    J. Exp. Med

    • G K Hirst
    • J. Exp. Med
    • 1943

    J. Gen. Virol

    • J M Daly
    • J. Gen. Virol
    • 1996

    J. Kruskal, Psychometrika

    • J. Kruskal, Psychometrika
    • 1964

    J. Theor. Biol

    • A Lapedes, R Farber
    • J. Theor. Biol
    • 2001