Mapping protein family interactions: intramolecular and intermolecular protein family interaction repertoires in the PDB and yeast.


In the postgenomic era, one of the most interesting and important challenges is to understand protein interactions on a large scale. The physical interactions between protein domains are fundamental to the workings of a cell: in multi-domain polypeptide chains, in multi-subunit proteins and in transient complexes between proteins that also exist… (More)


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