Mapping protein binding sites on the biomolecular corona of nanoparticles.

@article{Kelly2015MappingPB,
  title={Mapping protein binding sites on the biomolecular corona of nanoparticles.},
  author={Philip M. Kelly and Christoffer {\AA}berg and Ester Polo and Ann A. O'connell and Jennifer Cookman and Jonathan Fallon and Željka Krpeti{\'c} and Kenneth A. Dawson},
  journal={Nature nanotechnology},
  year={2015},
  volume={10 5},
  pages={
          472-9
        }
}
Nanoparticles in a biological milieu are known to form a sufficiently long-lived and well-organized 'corona' of biomolecules to confer a biological identity to the particle. Because this nanoparticle-biomolecule complex interacts with cells and biological barriers, potentially engaging with different biological pathways, it is important to clarify the presentation of functional biomolecular motifs at its interface. Here, we demonstrate that by using antibody-labelled gold nanoparticles… CONTINUE READING

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