Mapping physiological states from microarray expression measurements

@article{Stephanopoulos2002MappingPS,
  title={Mapping physiological states from microarray expression measurements},
  author={Gregory Stephanopoulos and Daehee Hwang and William A. Schmitt and Jatin Misra and George Stephanopoulos},
  journal={Bioinformatics},
  year={2002},
  volume={18 8},
  pages={1054-63}
}
MOTIVATION The increasing use of DNA microarrays to probe cell physiology requires methods for visualizing different expression phenotypes and explicitly connecting individual genes to discriminating expression features. Such methods should be robust and maintain biological interpretability. RESULTS We propose a method for the mapping of the physiological state of cells and tissues from multidimensional expression data such as those obtained with DNA microarrays. The method uses Fisher… CONTINUE READING

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