Mapping of the wet/dry earwax locus to the pericentromeric region of chromosome 16

  title={Mapping of the wet/dry earwax locus to the pericentromeric region of chromosome 16},
  author={Hiro-aki Tomita and K. Yamada and M. Ghadami and T. Ogura and N. Niikawa},
  journal={The Lancet},
Human earwax is a one-gene trait comprising two phenotypically distinct forms--wet and dry. This trait is attributed to secretory products of the ceruminous apocrine glands, and frequencies of phenotypes vary between ethnic groups. We did linkage analysis of eight Japanese families segregating earwax dimorphism. We assigned the earwax locus within a approximately 7.42-cM region between the loci D16S3093 and D16S3080 on chromosome 16p11.2-16q12.1, with a maximum two-point LOD score of 11.15… Expand
20 Citations
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