Mapping of the congenital generalized hypertrichosis locus to chromosome Xq24–q27.1

  title={Mapping of the congenital generalized hypertrichosis locus to chromosome Xq24–q27.1},
  author={L. Figuera and M. Pandolfo and P. Dunne and J. Cant{\'u} and P. Patel},
  journal={Nature Genetics},
  • L. Figuera, M. Pandolfo, +2 authors P. Patel
  • Published 1995
  • Biology, Medicine
  • Nature Genetics
  • Congenital generalized hypertrichosis (CGH) is a rare, fully penetrant X–linked dominant trait previously described in a single, multigenerational Mexican family. CGH is a visually striking phenotype characterized by excessive facial and upper torso hair in males and by less severe asymmetric hairiness in females. We have found significant evidence for linkage with several markers from the long arm of the X chromosome. Recombinant chromosomes place the CGH gene within a 22 cM interval between… CONTINUE READING
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