Mapping of the 12q12-q22 region with respect to tumor translocation breakpoints.

@article{Pedeutour1994MappingOT,
  title={Mapping of the 12q12-q22 region with respect to tumor translocation breakpoints.},
  author={Florence Pedeutour and Sandra Merscher and Eric Dominique Henri Durieux and Kate Montgomery and K. E. Krauter and J P Cl{\'e}vy and Gail Barcelo and Raju Kucherlapati and Patrick Gaudray and Claude Turc-Carel},
  journal={Genomics},
  year={1994},
  volume={22 3},
  pages={512-8}
}
The consistent involvement of the region 12q13-q15 in numerous human tumors speaks in favor of the presence of genes that may contribute to oncogenesis. Mapping genes within this region of chromosome 12 is a necessary step toward the identification of those that play a role in this process. We have undertaken a multiplex analysis using translocation breakpoint mapping to order from the centromere to the telomere a series of 24 loci from the region 12q12-q22. Thirteen adipose tissue tumors with… CONTINUE READING