Mapping of human apolipoprotein B antigenic determinants.

@article{Marcel1987MappingOH,
  title={Mapping of human apolipoprotein B antigenic determinants.},
  author={Yves L. Marcel and Thomas L. Innerarity and Charles H. Spilman and Robert W. Mahley and Andrew Asher Protter and Ross William Milne},
  journal={Arteriosclerosis},
  year={1987},
  volume={7 2},
  pages={
          166-75
        }
}
A minimum of 16 epitopes which provide a group of topographical markers to study the conformation of apolipoprotein (apo) B have been mapped in relation to elements of the sequence of apo B-100. Six of these epitopes are identified by monoclonal antibodies (Mabs) directed against low density lipoprotein (LDL) apo B, while at least 10 others react with Mabs obtained by immunization with delipidated and solubilized apo B. Five epitopes which are also expressed on apo B-48 have been assigned to… CONTINUE READING

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