Mapping of epitopes on the La(SS-B) autoantigen of primary Sjögren's syndrome: identification of a cross-reactive epitope.

Abstract

Autoepitopes on the ribonucleoprotein La(SS-B) were identified by using recombinant La(SS-B) polypeptides and sera from 166 patients with the antinuclear autoantibody anti-La(SS-B). The La(SS-B) polypeptides were encoded by polymerase chain reaction-derived overlapping or nonoverlapping fragments of the La(SS-B) gene, which encodes a protein of 408 amino… (More)

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Cite this paper

@article{McNeilage1990MappingOE, title={Mapping of epitopes on the La(SS-B) autoantigen of primary Sj{\"o}gren's syndrome: identification of a cross-reactive epitope.}, author={L Jane McNeilage and Elizabeth M Macmillan and Senga F. Whittingham}, journal={Journal of immunology}, year={1990}, volume={145 11}, pages={3829-35} }