Mapping of a new locus associated with autosomal recessive congenital cataract to chromosome 3q

PURPOSE To localize the disease interval for autosomal recessive congenital cataracts in a consanguineous Pakistani family. METHODS All affected individuals underwent detailed ophthalmologic examination. Blood samples were collected and genomic DNA was extracted. A genome-wide scan was performed with fluorescently-labeled microsatellite markers on genomic… (More)