Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors: definition of phenotypic groups.

@article{Courjal1997MappingOD,
  title={Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors: definition of phenotypic groups.},
  author={Frank Courjal and Marguerite Cuny and Jo{\"e}lle Simony-Lafontaine and G. Louason and Paul Speiser and Robert Zeillinger and Carmen Arbelo Rodr{\'i}guez and Charles Theillet},
  journal={Cancer research},
  year={1997},
  volume={57 19},
  pages={4360-7}
}
DNA amplification is frequent in breast cancer and has been associated with specific clinicopathological parameters and/or worsened course of the disease. In the present work, we were interested in further defining the association linking the occurrence of DNA amplification to the emergence of specific breast tumor phenotype. To this aim, we studied by Southern blotting a total of 1875 breast tumor DNAs with 26 probes mapping at 15 distinct chromosomal localizations. Of the 26 loci tested, 11… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 49 references

Two distinct amplified regions at 17 q 11 †” q 21 involved in human primary breast cancer

C. H. gnier, C. Moog-Lutz, M-C. Rio, R. Lidereau
Cancer Res . • 1996

l 7 @Estradiol induces cyclin Dl gene transcription , p 36 Dl†” p 34 cdk 4 complex activation , and pIOSRb phosphorylation dur ing mitogenic stimulation of G 1arrested human breast cancer cells

L. Altucci, R. Addeo, +7 authors A. Weisz
Oncogene • 1996

lute grated map of the chromosome 8 pl 2 †” p 2 lregion , a region involved in human cancers and Wemer syndrome

H. Sobol, M-J. busque
Genomics • 1996

Amplification of chromosomal region 20q13 in invasive breast cancer: prognostic implications.

Clinical cancer research : an official journal of the American Association for Cancer Research • 1995

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