Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

@inproceedings{Folkersen2017MappingO7,
  title={Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease},
  author={Lasse Folkersen and Eric Fauman and Maria Sabater-Lleal and Rona J. Strawbridge and Mattias Fr{\aa}nberg and Bengt Sennblad and Damiano Baldassarre and Fabrizio Veglia and Steve E Humphries and Rainer Rauramaa and Ulf de Faire and Andries J. Smit and Philippe Giral and S Kurl and Elmo Mannarino and Stefan Enroth and {\AA}sa Johansson and Sofia Bosdotter Enroth and Stefan Gustafsson and Lars Lind and Cecilia M. Lindgren and Andrew P. Morris and Vilmantas Giedraitis and Angela Silveira and Anders Franco-Cereceda and Elena Tremoli and Ulf Gyllensten and Erik Ingelsson and S{\o}ren Brunak and Per Eriksson and Daniel Ziemek and Anders Hamsten and Anders M{\"a}larstig},
  booktitle={PLoS genetics},
  year={2017}
}
Recent advances in highly multiplexed immunoassays have allowed systematic large-scale measurement of hundreds of plasma proteins in large cohort studies. In combination with genotyping, such studies offer the prospect to 1) identify mechanisms involved with regulation of protein expression in plasma, and 2) determine whether the plasma proteins are likely to be causally implicated in disease. We report here the results of genome-wide association (GWA) studies of 83 proteins considered relevant… CONTINUE READING
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