Mapping of 5-HT2A receptors and their mRNA in monkey brain: [3H]MDL100,907 autoradiography and in situ hybridization studies.

@article{LpezGimnez2001MappingO5,
  title={Mapping of 5-HT2A receptors and their mRNA in monkey brain: [3H]MDL100,907 autoradiography and in situ hybridization studies.},
  author={Juan Francisco L{\'o}pez-Gim{\'e}nez and Maria Teresa Vilar{\'o} and Jos{\`e} Maria Palacios and Guadalupe Mengod},
  journal={The Journal of comparative neurology},
  year={2001},
  volume={429 4},
  pages={571-89}
}
The anatomic distribution of serotonin 5-HT2A receptors visualized with [3H]MDL100,907 and of their mRNA detected by in situ hybridization were studied in monkey brain. Both autoradiographic patterns of signal showed heterogeneous distributions and were in general in good agreement in the majority of brain regions. In most neocortical areas, [3H]MDL100,907 presented a four-banded pattern with layers I and III-IV more intensely labeled and layers II and V-VI showing weaker labeling. 5-HT2A… CONTINUE READING
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