Mapping mutations on phylogenies.

  title={Mapping mutations on phylogenies.},
  author={R. Nielsen},
  journal={Systematic biology},
  volume={51 5},
Mapping of mutations on a phylogeny has been a commonly used analytical tool in phylogenetics and molecular evolution. However, the common approaches for mapping mutations based on parsimony have lacked a solid statistical foundation. Here, I present a Bayesian method for mapping mutations on a phylogeny. I illustrate some of the common problems associated with using parsimony and suggest instead that inferences in molecular evolution can be made on the basis of the posterior distribution of… CONTINUE READING
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