Mapping joint grey and white matter reductions in Alzheimer's disease using joint independent component analysis.

@article{Guo2012MappingJG,
  title={Mapping joint grey and white matter reductions in Alzheimer's disease using joint independent component analysis.},
  author={Xiaojuan Guo and Yuan Han and Kewei Chen and Yan Wang and Li Yao},
  journal={Neuroscience letters},
  year={2012},
  volume={531 2},
  pages={136-41}
}
Alzheimer's disease (AD) is a neurodegenerative disease concomitant with grey and white matter damages. However, the interrelationship of volumetric changes between grey and white matter remains poorly understood in AD. Using joint independent component analysis, this study identified joint grey and white matter volume reductions based on structural magnetic resonance imaging data to construct the covariant networks in twelve AD patients and fourteen normal controls (NC). We found that three… CONTINUE READING

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