Mapping calcium phosphate activated gene networks as a strategy for targeted osteoinduction of human progenitors.

@article{Eyckmans2013MappingCP,
  title={Mapping calcium phosphate activated gene networks as a strategy for targeted osteoinduction of human progenitors.},
  author={Jeroen Eyckmans and Scott J Roberts and Johanna Bolander and Jan Schrooten and Christopher S. Chen and Frank P. Luyten},
  journal={Biomaterials},
  year={2013},
  volume={34 19},
  pages={4612-21}
}
Although calcium phosphate-containing biomaterials are promising scaffolds for bone regenerative strategies, the osteoinductive capacity of such materials is poorly understood. In this study, we investigated whether endogenous mechanisms of in vivo calcium phosphate-driven, ectopic bone formation could be identified and used to induce enhanced… CONTINUE READING