Mapping brain regions in which deep brain stimulation affects schizophrenia-like behavior in two rat models of schizophrenia.

@article{Klein2013MappingBR,
  title={Mapping brain regions in which deep brain stimulation affects schizophrenia-like behavior in two rat models of schizophrenia.},
  author={Julia Klein and Ravit Hadar and Thomas Goetz and Anika M{\"a}nner and Claudia Eberhardt and Jacopo Baldassarri and Timo Torsten Schmidt and Andreas Kupsch and Andreas Heinz and Rudolf Morgenstern and Miriam Schneider and Ina Weiner and Christine Winter},
  journal={Brain stimulation},
  year={2013},
  volume={6 4},
  pages={490-9}
}
BACKGROUND AND OBJECTIVES The development of more efficient treatment remains a major unmet need in the realm of schizophrenia disease. Using the maternal immune stimulation and the pubertal cannabinoid administration rat model of schizophrenia, the present study aimed at testing the hypothesis that deep brain stimulation (DBS) serves as a novel therapeutic technique for this disorder. METHODS Adult offspring of dams, treated with the immune activating agent poly I:C (4 mg/kg, n = 50) or… CONTINUE READING