Mapping and comprehensive analysis of the extracellular and cell surface proteome of the human pathogen Corynebacterium diphtheriae

  title={Mapping and comprehensive analysis of the extracellular and cell surface proteome of the human pathogen Corynebacterium diphtheriae},
  author={Nicole Hansmeier and Tzu-Chiao Chao and J{\"o}rn Kalinowski and Alfred P{\"u}hler and Andreas Tauch},
Secreted proteins of the human pathogen Corynebacterium diphtheriae might be involved in important pathogen–host cell interactions. Here, we present the first systematic reference map of the extracellular and cell surface proteome fractions of the type strain C. diphtheriae C7s(‐)tox‐. The analysis window of 2‐DE covered the pI range from 3 to 10 along with a MW range from 8 to 150 kDa. Computational analysis of the 2‐D gels detected almost 150 protein spots in the extracellular proteome… 
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