Mapping Transcription Regulatory Networks with ChIP-seq and RNA-seq.

@article{Wade2015MappingTR,
  title={Mapping Transcription Regulatory Networks with ChIP-seq and RNA-seq.},
  author={Joseph T Wade},
  journal={Advances in experimental medicine and biology},
  year={2015},
  volume={883},
  pages={119-34}
}
Bacterial genomes encode numerous transcription factors, DNA-binding proteins that regulate transcription initiation. Identifying the regulatory targets of transcription factors is a major challenge of systems biology. Here I describe the use of two genome-scale approaches, ChIP-seq and RNA-seq, that are used to map transcription factor regulons. ChIP-seq… CONTINUE READING