Mapping Reads on a Genomic Sequence: An Algorithmic Overview and a Practical Comparative Analysis

Abstract

Mapping short reads against a reference genome is classically the first step of many next-generation sequencing data analyses, and it should be as accurate as possible. Because of the large number of reads to handle, numerous sophisticated algorithms have been developped in the last 3 years to tackle this problem. In this article, we first review the… (More)
DOI: 10.1089/cmb.2012.0022

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