Mapping Genetically Compensatory Pathways from Synthetic Lethal Interactions in Yeast

Abstract

BACKGROUND Synthetic lethal genetic interaction analysis has been successfully applied to predicting the functions of genes and their pathway identities. In the context of synthetic lethal interaction data alone, the global similarity of synthetic lethal interaction patterns between two genes is used to predict gene function. With physical interaction data… (More)
DOI: 10.1371/journal.pone.0001922

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@article{Ma2008MappingGC, title={Mapping Genetically Compensatory Pathways from Synthetic Lethal Interactions in Yeast}, author={Xiaotu Ma and Aaron M. Tarone and Wenyuan Li}, journal={PLoS ONE}, year={2008}, volume={3}, pages={561 - 566} }