Mapping Compulsivity in the DSM-5 Obsessive Compulsive and Related Disorders: Cognitive Domains, Neural Circuitry, and Treatment

  title={Mapping Compulsivity in the DSM-5 Obsessive Compulsive and Related Disorders: Cognitive Domains, Neural Circuitry, and Treatment},
  author={Naomi Anne Fineberg and A. Apergis-Schoute and Matilde Maria Serena Vaghi and Paula Banca and Claire M. Gillan and Valerie Voon and Samuel R. Chamberlain and Eduardo Cinosi and Jemma Reid and Sonia Shahper and Edward T. Bullmore and Barbara Jacquelyn Sahakian and Trevor William Robbins},
  journal={International Journal of Neuropsychopharmacology},
  pages={42 - 58}
Abstract Compulsions are repetitive, stereotyped thoughts and behaviors designed to reduce harm. Growing evidence suggests that the neurocognitive mechanisms mediating behavioral inhibition (motor inhibition, cognitive inflexibility) reversal learning and habit formation (shift from goal-directed to habitual responding) contribute toward compulsive activity in a broad range of disorders. In obsessive compulsive disorder, distributed network perturbation appears focused around the prefrontal… 

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