Many new down- and up-regulatory signaling pathways, from known cancer progression suppressors to matrix metalloproteinases, differ widely in cells of various cancers.

@article{Delassus2010ManyND,
  title={Many new down- and up-regulatory signaling pathways, from known cancer progression suppressors to matrix metalloproteinases, differ widely in cells of various cancers.},
  author={Gregory S Delassus and Hyojin Cho and Stanley Hoang and George L Eliceiri},
  journal={Journal of cellular physiology},
  year={2010},
  volume={224 2},
  pages={549-58}
}
Previously we detected new signaling pathways, some downregulatory and others upregulatory, from seven known suppressors of cancer progression to the expression of eight cancer-promoting matrix metalloproteinases (MMPs) in breast cancer cells. The goals of the present study were to test whether the preceding observations occur only in breast cancer cells and, if not, whether the same downregulatory and upregulatory signaling pathways are active in cells of other human cancers, focusing on… CONTINUE READING

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