Many faces of orexin/hypocretin.


Orexin/hypocretin (ORX/Hcrt) is a neuropeptide discovered in 1998 that is produced by a small group of neurons exclusively localized to the hypothalamus with extensive CNS wide projections. These neurons appear to regulate a wide range of homeostatic functions. Much innovative research has emerged in this field over the past decade, and several novel drug… (More)
DOI: 10.1016/B978-0-444-59489-1.00019-7