Many different papillomaviruses have low transcriptional activity in spite of strong epithelial specific enhancers.

Abstract

Transcription of the E6-E7 genes of human papillomavirus type 11 (HPV-11), HPV-16 and HPV-18 is specific to epithelial cells. This mechanism originates from synergism between different transcription factors such as AP-1, NFI and Sp1, which occur in many different cell types, but whose activity is biased in favour of epithelial cells. In this study, the… (More)

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Cite this paper

@article{Sailaja1999ManyDP, title={Many different papillomaviruses have low transcriptional activity in spite of strong epithelial specific enhancers.}, author={Gangadhara Sailaja and Reid M. Watts and Hans U Bernard}, journal={The Journal of general virology}, year={1999}, volume={80 ( Pt 7)}, pages={1715-24} }