Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium

@inproceedings{Zou2010ManufacturingAI,
  title={Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium},
  author={Jing Zou and Rohit Sood and Sanjeev M. Ranjan and Dennis Poe and Usama Abo Ramadan and Paavo K. J. Kinnunen and Ilmari Pyykk{\"o}},
  booktitle={Journal of nanobiotechnology},
  year={2010}
}
BackgroundTreatment of inner ear diseases remains a problem because of limited passage through the blood-inner ear barriers and lack of control with the delivery of treatment agents by intravenous or oral administration. As a minimally-invasive approach, intratympanic delivery of multifunctional nanoparticles (MFNPs) carrying genes or drugs to the inner ear is a future therapy for treating inner ear diseases, including sensorineural hearing loss (SNHL) and Meniere's disease. In an attempt to… CONTINUE READING
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Inner ear barriers to nanomedicine-augmented drug delivery and imaging☆

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