Mannosylated biodegradable polyethyleneimine for targeted DNA delivery to dendritic cells

@inproceedings{Sun2012MannosylatedBP,
  title={Mannosylated biodegradable polyethyleneimine for targeted DNA delivery to dendritic cells},
  author={Xun Sun and Simu Chen and Jianfeng Han and Zhirong Zhang},
  booktitle={International journal of nanomedicine},
  year={2012}
}
  • Xun Sun, Simu Chen, +1 author Zhirong Zhang
  • Published in
    International journal of…
    2012
  • Medicine, Materials Science
  • BACKGROUND To establish a potential gene-delivery system with the ability to deliver plasmid DNA to dendritic cells (DCs) more efficiently and specifically, we designed and synthesized a low-molecular-weight polyethyleneimine and triethyleneglycol polymer (PEI-TEG) and a series of its mannosylated derivatives. METHODS PEI-TEG was synthesized from PEI2000 and PEI600 with TEG as the cross-linker. PEI-TEG was then linked to mannose via a phenylisothiocyanate bridge to obtain man-PEI-TEG… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 13 CITATIONS

    Glycosylation-mediated targeting of carriers.

    VIEW 6 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Glycyrrhizin Acid and Glycyrrhetinic Acid Modified Polyethyleneimine for Targeted DNA Delivery to Hepatocellular Carcinoma

    VIEW 1 EXCERPT
    CITES BACKGROUND

    A mannosylated cell-penetrating peptide-graft-polyethylenimine as a gene delivery vector.

    VIEW 1 EXCERPT
    CITES BACKGROUND

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 37 REFERENCES

    Comprehensive comparison of two new biodegradable gene carriers.

    VIEW 5 EXCERPTS

    Intracellular DNA release and elimination correlate poorly with transgene expression after non-viral transfection.

    VIEW 1 EXCERPT

    Nonviral vectors for gene delivery.

    VIEW 1 EXCERPT