Mannosyl-Recognizing Receptors Induce an M1-Like Phenotype in Macrophages of Susceptible Mice but an M2-Like Phenotype in Mice Resistant to a Fungal Infection

@inproceedings{Feriotti2013MannosylRecognizingRI,
  title={Mannosyl-Recognizing Receptors Induce an M1-Like Phenotype in Macrophages of Susceptible Mice but an M2-Like Phenotype in Mice Resistant to a Fungal Infection},
  author={Cl{\'a}udia Feriotti and Fl{\'a}vio Vieira Loures and Eliseu Frank de Ara{\'u}jo and Tania Alves da Costa and Vera L G Calich},
  booktitle={PloS one},
  year={2013}
}
In addition to alpha1,3 glucan, mannan and mannan-linked proteins are expressed in the outer layer of Paracoccidioides brasiliensis yeasts. The recognition of mannosyl residues by multiple pathogen recognition receptors, such as the mannose receptor (MR), complement receptor 3 (CR3) and toll-like receptor 4 (TLR4) on macrophage membranes can influence macrophage activation and the mechanisms of innate immunity against fungal pathogens. The aim of this study was to clarify the role of these… CONTINUE READING
Highly Cited
This paper has 27 citations. REVIEW CITATIONS
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 70 references

Innate Recognition of Fungal Cell Walls

PLoS pathogens • 2010
View 6 Excerpts
Highly Influenced

TLR4 signaling leads to a more severe fungal infection associated with enhanced proinflammatory immunity and impaired expansion of regulatory T cells

FV Loures, A Pina, M Felonato, EF Araújo, KR Leite
Infec Immun • 2010
View 4 Excerpts
Highly Influenced

Pathogen recognition by innate receptors.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy • 2008
View 5 Excerpts
Highly Influenced

Recognition of fungal by tool-like receptors

MG Netea, G Ferwerda, CA Van Der Graaf, JW Van Der Meer, BJ Kullberg
Curr Pharm Des • 2006
View 4 Excerpts
Highly Influenced

How C-type lectins detect pathogens.

Cellular microbiology • 2005
View 5 Excerpts
Highly Influenced

Macrophage receptors and immune recognition.

Annual review of immunology • 2005
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…