Mannose-binding lectin in chronic hepatitis B virus infection.

  title={Mannose-binding lectin in chronic hepatitis B virus infection.},
  author={Wai Po Chong and Yuk Fai To and Wai Kee Ip and Man Fung Yuen and Tung Ping Poon and Wilfred Hing Sang Wong and Ching Lung Lai and Yu Lung Lau},
  volume={42 5},
Mannose binding lectin (MBL) is a pattern-recognition molecule of the innate immune system. The roles of MBL and its gene (mbl2) polymorphisms, -221X/Y and codon 54A/B, in hepatitis B virus (HBV) infection were investigated in this study. We recruited 320 nonprogressed hepatitis B surface antigen (HBsAg) carriers; 199 progressed HBsAg carriers with hepatocellular carcinoma or cirrhosis; 87 spontaneously recovered individuals who were HBsAg negative and anti-HBs and anti HBc positive; and 484… CONTINUE READING
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