Mannose-binding lectin gene polymorphisms in Brazilian patients with rheumatoid arthritis.

@article{Martiny2012MannosebindingLG,
  title={Mannose-binding lectin gene polymorphisms in Brazilian patients with rheumatoid arthritis.},
  author={Fernanda Let{\'i}cia Martiny and Tiago Veit and Claiton Viegas Brenol and Jo{\~a}o Carlos Tavares Brenol and Ricardo Machado Xavier and Maur{\'i}cio Reis Bogo and Jos{\'e} Artur Bogo Chies},
  journal={The Journal of rheumatology},
  year={2012},
  volume={39 1},
  pages={
          6-9
        }
}
OBJECTIVE Rheumatoid arthritis (RA) is a disease with unknown etiology but it is probably multifactorial. RA susceptibility is related to genetic, hormonal, immunologic, and environmental factors. Mannose-binding lectin (MBL) is an important protein of the human innate immune system, encoded by the MBL2 gene. Polymorphisms in MBL2 were associated with several diseases, and may be an important factor in RA susceptibility. We analyzed 3 MBL2 gene polymorphisms in 322 Brazilian patients with RA… CONTINUE READING

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