Mannose-binding lectin and Toll-like receptor polymorphisms and Chagas disease in Chile.

@article{Weitzel2012MannosebindingLA,
  title={Mannose-binding lectin and Toll-like receptor polymorphisms and Chagas disease in Chile.},
  author={Thomas Weitzel and In{\'e}s Zulantay and Ina Danquah and Lutz Hamann and R. Randall Schumann and Werner Apt and Frank P Mockenhaupt},
  journal={The American journal of tropical medicine and hygiene},
  year={2012},
  volume={86 2},
  pages={229-32}
}
Mannose-binding lectin (MBL) and Toll-like receptor (TLR) polymorphisms may influence susceptibility and manifestation of Trypanosoma cruzi infection. In northern Chile, we examined 61 asymptomatic patients with chronic Chagas disease (CD), 64 patients with chronic Chagas cardiomyopathy (CCC), and 45 healthy individuals. Low-producer MBL2*B genotypes were more common in CD patients (48%) than healthy individuals (31%; adjusted odds ratio = 2.3, 95% confidence interval = 1.01-5.4, P = 0.047) but… CONTINUE READING
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