Mannose Receptor and Its Putative Ligands in Normal Murine Lymphoid and Nonlymphoid Organs: In Situ Expression of Mannose Receptor by Selected Macrophages, Endothelial Cells, Perivascular Microglia, and Mesangial Cells, but not Dendritic Cells

@article{Linehan1999MannoseRA,
  title={Mannose Receptor and Its Putative Ligands in Normal  Murine Lymphoid and Nonlymphoid Organs: In Situ  Expression of Mannose Receptor by Selected Macrophages,  Endothelial Cells, Perivascular Microglia, and Mesangial  Cells, but not Dendritic Cells },
  author={Sheena A. Linehan and Luisa Martinez-Pomares and Philip D. Stahl and Siamon Gordon},
  journal={The Journal of Experimental Medicine},
  year={1999},
  volume={189},
  pages={1961 - 1972}
}
The mannose receptor (MR) has established roles in macrophage (Mphi) phagocytosis of microorganisms and endocytic clearance of host-derived glycoproteins, and has recently been implicated in antigen capture by dendritic cells (DCs) in vitro. MR is the founder member of a family of homologous proteins, and its recognition properties differ according to its tissue of origin. Given this heterogeneity and our recent discovery of a soluble form of MR in mouse serum, we studied the sites of synthesis… CONTINUE READING

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A cysteine-rich domain of the "mannose" receptor mediates GalNAc-4-SO4 binding.

Proceedings of the National Academy of Sciences of the United States of America • 1998
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