Mannan-binding lectin: clinical significance and applications.

@article{Kilpatrick2002MannanbindingLC,
  title={Mannan-binding lectin: clinical significance and applications.},
  author={David Chalmers Kilpatrick},
  journal={Biochimica et biophysica acta},
  year={2002},
  volume={1572 2-3},
  pages={401-13}
}
Mannan-binding lectin (MBL) is a collectin (protein with both collagen-like and C-type lectin domains) synthesised in the liver and secreted into the bloodstream. Its plasma concentration is for the most part genetically determined by a series of allelic dimorphisms located both in the structural gene and in the promoter region. Genotypes made up of combinations of seven haplotypes are mainly responsible for a 1000-fold concentration variation found in human beings. MBL is a pattern recognition… CONTINUE READING

From This Paper

Topics from this paper.
77 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 77 extracted citations

Similar Papers

Loading similar papers…