Manipulation of the host protein acetylation network by human immunodeficiency virus type 1.

@article{Jeng2015ManipulationOT,
  title={Manipulation of the host protein acetylation network by human immunodeficiency virus type 1.},
  author={Mark Y Jeng and Ibraheem Ali and Melanie Ott},
  journal={Critical reviews in biochemistry and molecular biology},
  year={2015},
  volume={50 4},
  pages={314-25}
}
Over the past 15 years, protein acetylation has emerged as a globally important post-translational modification that fine-tunes major cellular processes in many life forms. This dynamic regulatory system is critical both for complex eukaryotic cells and for the viruses that infect them. HIV-1 accesses the host acetylation network by interacting with several key enzymes, thereby promoting infection at multiple steps during the viral life cycle. Inhibitors of host histone deacetylases and… CONTINUE READING
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