• DOI:10.1016/j.neurobiolaging.2007.01.013
Corpus ID: 37671716

Manipulation of serotonin signal suppresses early phase of behavioral aging in Caenorhabditis elegans

@article{Murakami2008ManipulationOS,
  title={Manipulation of serotonin signal suppresses early phase of behavioral aging in Caenorhabditis elegans},
  author={Hana Murakami and Karalee Bessinger and J. Hellmann and S. Murakami},
  journal={Neurobiology of Aging},
  year={2008},
  volume={29},
  pages={1093-1100}
}

Hana Murakami, Karalee Bessinger, +1 author S. Murakami

Published 2008

Biology, Medicine

Neurobiology of Aging

Aging is associated with progressive changes in behavioral functions, in part caused by muscle frailty, called sarcopenia. However, it was not clear whether certain neurotransmitters are directly involved in behavioral aging. Here we investigated aging of locomotion behaviors with an associative learning property, called basal and enhanced slowing response in Caenorhabditis elegans. Basal slowing response is a modest slowdown in response to food, while enhanced slowing response is a greater… CONTINUE READING

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