Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors.

@article{Ge2011ManipulationOH,
  title={Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors.},
  author={Jianning Ge and Feng Shao},
  journal={Cellular microbiology},
  year={2011},
  volume={13 12},
  pages={
          1870-80
        }
}
Legionella pneumophila, the causative agent of Legionnaires' disease, infects and replicates in macrophages and amoebas. Following internalization, L. pneumophila resides in a vacuole structure called Legionella-containing vacuole (LCV). The LCV escapes from the endocytic maturation process and avoids fusion with the lysosome, a hallmark of Legionella pathogenesis. Interference with the secretory vesicle transport and avoiding lysosomal targeting render the LCV permissive for L. pneumophila… CONTINUE READING
BETA
Highly Cited
This paper has 40 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 28 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 95 REFERENCES

Similar Papers

Loading similar papers…