Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer.

@article{Kwon1997ManipulationOT,
  title={Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer.},
  author={Eugene D. Kwon and Arthur A. Hurwitz and Barbara A. Foster and Christopher Madias and Andrew L Feldhaus and Norman M. Greenberg and Maurice B. Burg and James P Allison},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1997},
  volume={94 15},
  pages={8099-103}
}
The identification of potentially useful immune-based treatments for prostate cancer has been severely constrained by the scarcity of relevant animal research models for this disease. Moreover, some of the most critical mechanisms involved in complete and proper antitumoral T cell activation have only recently been identified for experimental manipulation, namely, components involved in the costimulatory pathway for T cell activation. Thus, we have established a novel syngeneic murine prostate… CONTINUE READING

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Kwon et al

D. W. Keetch, Andriole, +16 authors experiments in B were performed two times. 8102 Medical Sciences
Proc. Natl. Acad. Sci. USA 94 • 1997

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