Manipulating prohibitin levels provides evidence for an in vivo role in androgen regulation of prostate tumours


Current hormonal therapies for prostate cancer are effective initially, but inevitably tumours progress to an advanced, metastatic stage, often referred to as 'androgen independent'. However, the androgen receptor (AR) signalling pathway is still key for their growth. It is speculated that tumours escape hormonal control via reduction in corepressor… (More)
DOI: 10.1677/ERC-09-0028


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