Manipulating megakaryocytes to manufacture platelets ex vivo


Historically, platelet transfusion has proven a reliable way to treat patients suffering from thrombocytopenia or similar ailments. An undersupply of donors, however, has demanded alternative platelet sources. Scientists have therefore sought to recapitulate the biological events that convert hematopoietic stem cells into platelets in the laboratory. Such… (More)
DOI: 10.1111/jth.12946


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Citations per Year

Citation Velocity: 6

Averaging 6 citations per year over the last 2 years.

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