Mania induced by tricyclic-MAOI combination therapy in bipolar treatment-resistant disorder: case reports.

Abstract

Three patients with bipolar disorder developed manic symptoms while receiving a combination of isocarboxazid and amitriptyline during an episode of major depression refractory to previous treatments. It is suggested that mania be considered a possible complication of combined treatment with an MAO inhibitor and a tricyclic antidepressant.

Cite this paper

@article{Fuente1986ManiaIB, title={Mania induced by tricyclic-MAOI combination therapy in bipolar treatment-resistant disorder: case reports.}, author={Jorge Ruiz de la Fuente and Carlos Berlanga and C Le{\'o}n-Andrade}, journal={The Journal of clinical psychiatry}, year={1986}, volume={47 1}, pages={40-1} }