Manganese superoxide dismutase induced by TNF-beta is regulated transcriptionally by NF-kappaB after spinal cord injury in rats.

@article{Yune2004ManganeseSD,
  title={Manganese superoxide dismutase induced by TNF-beta is regulated transcriptionally by NF-kappaB after spinal cord injury in rats.},
  author={Tae Young Yune and Sang Mi Lee and Sun Jung Kim and Hong Kyu Park and Young Jun Oh and Young Choong Kim and George J. Markelonis and Tae Hwan Oh},
  journal={Journal of neurotrauma},
  year={2004},
  volume={21 12},
  pages={1778-94}
}
Antioxidant enzymes including superoxide dismutase (SOD) may play a role in the mechanism by which cells counteract the deleterious effects of reactive oxygen species (ROS) after spinal cord injury (SCI). Cu/Zn and MnSOD are especially potent scavengers of superoxide anion and likely serve important cytoprotective roles against cellular damage. We investigated expression of SOD after SCI to address its role during the early stages of injury. MnSOD activity was increased 4 h after SCI and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…