Manganese poisoning and the attack of trivalent manganese upon catecholamines.

@article{Archibald1987ManganesePA,
  title={Manganese poisoning and the attack of trivalent manganese upon catecholamines.},
  author={Frederick S Archibald and Curtis M Tyree},
  journal={Archives of biochemistry and biophysics},
  year={1987},
  volume={256 2},
  pages={638-50}
}
Human manganese poisoning or manganism results in damage to the substantia nigra of the brain stem, a drop in the level of the inhibitory neurotransmitter dopamine, and symptoms resembling those of Parkinson's disease. Manganic (Mn3+) manganese ions were shown to be readily produced by O-2 in vitro and spontaneously under conditions obtainable in the human… CONTINUE READING