Manganese metabolism is impaired in the Belgrade laboratory rat

  title={Manganese metabolism is impaired in the Belgrade laboratory rat},
  author={Anita C. G. Chua and Evan H. Morgan},
  journal={Journal of Comparative Physiology B},
Homozygous Belgrade rats have a hypochromic anaemia due to impaired iron transport across the cell membrane of immature erythroid cells. This study aimed at investigating whether there are also abnormalities of Mn metabolism in erythroid and other types of cells. The experiments were performed with homozygous (b/b) and heterozygous (+/b) Belgrade rats and Wistar rats and included measurements of Mn uptake by reticulocytes in vitro, Mn absorption from in situ closed loops of the duodenum, and… CONTINUE READING


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Manganese In: Mertz W (ed) Trace elements in human and animal nutrition

  • LS Hurley, CL Keen
  • 1987
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