Manganese intake and cholestatic jaundice in neonates receiving parenteral nutrition: a randomized controlled study.

@article{Fok2001ManganeseIA,
  title={Manganese intake and cholestatic jaundice in neonates receiving parenteral nutrition: a randomized controlled study.},
  author={Tai Fai Fok and Kevin K. Chui and R Cheung and Pak Cheung Ng and Kam Lau Cheung and Magnus Hjelm},
  journal={Acta paediatrica},
  year={2001},
  volume={90 9},
  pages={
          1009-15
        }
}
UNLABELLED Infants requiring parenteral nutrition (n = 244) were randomized to receive either 1 (group 1, n = 121) or 0.0182 micromol/kg/d (group 2, n = 123) of manganese supplementation. The whole-blood manganese and serum direct bilirubin concentrations of the infants were monitored, as was the development of cholestasis (peak serum direct bilirubin concentration >50 micromol/L). Subgroup analysis was carried out on the data of 78 infants in group 1 and 82 in group 2 who had received… CONTINUE READING

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