Manganese-dependent disproportionation of hydrogen peroxide in bicarbonate buffer.

@article{Stadtman1990ManganesedependentDO,
  title={Manganese-dependent disproportionation of hydrogen peroxide in bicarbonate buffer.},
  author={Earl R. Stadtman and Barbara S. Berlett and P. Boon Chock},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1990},
  volume={87 1},
  pages={384-8}
}
At physiological concentrations of HCO3- and CO2, Mn(II) catalyzes disproportionation of H2O2. This catalase-like activity is directly proportional to the concentrations of Mn(II) and H2O2, and it increases exponentially with increases in pH. The effect of increasing pH is almost completely attributable to the concomitant increase in HCO3- concentration. The rate is proportional to the third power of the HCO3- concentration, suggesting that 3 equivalents of HCO3- combine with 1 equivalent of Mn… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

Similar Papers

Loading similar papers…