Manganese acts centrally to stimulate luteinizing hormone secretion: a potential influence on female pubertal development.

@article{Pine2005ManganeseAC,
  title={Manganese acts centrally to stimulate luteinizing hormone secretion: a potential influence on female pubertal development.},
  author={Michelle Pine and Boyeon Lee and Robert K. Dearth and Jill K Hiney and William Dees},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2005},
  volume={85 2},
  pages={
          880-5
        }
}
Manganese (Mn), an essential element considered important for normal growth and reproduction, has been shown in adults to be detrimental to reproductive function when elevated. Because Mn can cross the blood-brain barrier and accumulate in the hypothalamus, and because it has been suggested that infants and children are potentially more sensitive to Mn than adults, we wanted to determine the effects of Mn exposure on puberty-related hormones and the onset of female puberty. We demonstrated that… CONTINUE READING

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References

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SHOWING 1-10 OF 38 REFERENCES

Disorders of puberty

  • P. A. Lee
  • Pediatric Endocrinology (
  • 1996
Highly Influential
3 Excerpts

The timing of normal puberty and the age limits of sexual precocity: Variations around the world, secular trends and changes after migration

  • A. S. Parent, G. Teilman, A. Fuul, N. E. Skakkebaek, J. Toppar, J. P. Bourguignon
  • Endo. Rev
  • 2003
Highly Influential
4 Excerpts

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