Manganese action in brain function

@article{Takeda2003ManganeseAI,
  title={Manganese action in brain function},
  author={A. Takeda},
  journal={Brain Research Reviews},
  year={2003},
  volume={41},
  pages={79-87}
}
  • A. Takeda
  • Published 2003
  • Biology, Medicine
  • Brain Research Reviews
Manganese, an essential trace metal, is supplied to the brain via both the blood-brain and the blood-cerebrospinal fluid barriers. There are some mechanisms in this process and transferrin may be involved in manganese transport into the brain. A large portion of manganese is bound to manganese metalloproteins, especially glutamine synthetase in astrocytes. A portion of manganese probably exists in the synaptic vesicles in glutamatergic neurons and the manganese is dynamically coupled to the… Expand
467 Citations
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