• DOI:10.1016/S0165-0173(02)00234-5
Corpus ID: 1922613

Manganese action in brain function

@article{Takeda2003ManganeseAI,
  title={Manganese action in brain function},
  author={A. Takeda},
  journal={Brain Research Reviews},
  year={2003},
  volume={41},
  pages={79-87}
}

• A. Takeda
• Published 2003
• Biology, Medicine
• Brain Research Reviews

Manganese, an essential trace metal, is supplied to the brain via both the blood-brain and the blood-cerebrospinal fluid barriers. There are some mechanisms in this process and transferrin may be involved in manganese transport into the brain. A large portion of manganese is bound to manganese metalloproteins, especially glutamine synthetase in astrocytes. A portion of manganese probably exists in the synaptic vesicles in glutamatergic neurons and the manganese is dynamically coupled to the… Expand

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