Manduca sexta lipopolysaccharide-specific immulectin-2 protects larvae from bacterial infection.

@article{Yu2003ManducaSL,
  title={Manduca sexta lipopolysaccharide-specific immulectin-2 protects larvae from bacterial infection.},
  author={Xiao-qiang Yu and Michael R. Kanost},
  journal={Developmental and comparative immunology},
  year={2003},
  volume={27 3},
  pages={189-96}
}
We previously reported the isolation of a lipopolysaccharide (LPS)-specific immulectin-2 from the tobacco hornworm, Manduca sexta [J. Biol. Chem. 275 (2000) 37373]. Immulectin-2 is a C-type lectin that is present at a constitutively low level in hemolymph of naive larvae, and its synthesis is induced after injection of Gram-negative bacteria or LPS. Immulectin-2 contains two carbohydrate recognition domains. It binds to LPS and stimulates prophenoloxidase activation in plasma. In this paper, we… CONTINUE READING

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