Managing membrane stress: the phage shock protein (Psp) response, from molecular mechanisms to physiology.

@article{Joly2010ManagingMS,
  title={Managing membrane stress: the phage shock protein (Psp) response, from molecular mechanisms to physiology.},
  author={Nicolas Joly and Christoph Engl and Goran Jovanovic and Maxime Huvet and Tina Toni and Xia Sheng and Michael P. H. Stumpf and Martin Buck},
  journal={FEMS microbiology reviews},
  year={2010},
  volume={34 5},
  pages={797-827}
}
The bacterial phage shock protein (Psp) response functions to help cells manage the impacts of agents impairing cell membrane function. The system has relevance to biotechnology and to medicine. Originally discovered in Escherichia coli, Psp proteins and homologues are found in Gram-positive and Gram-negative bacteria, in archaea and in plants. Study of the E. coli and Yersinia enterocolitica Psp systems provides insights into how membrane-associated sensory Psp proteins might perceive membrane… CONTINUE READING